ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Apoptosis > p53 activator > Tenovin-6
Tenovin-6
Tenovin-6 Basic information
- Product Name:
- Tenovin-6
- Synonyms:
-
- Tenovin-6
- 4-TERT-BUTYL-N-(4-(5-(DIMETHYLAMINO)PENTANAMIDO)PHENYLCARBAMOTHIOYL)BENZAMIDE HYDROCHLORIDE
- N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide
- Benzamide, N-[[[4-[[5-(dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-
- N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide Tenovin-6
- Tenovin-6, 98%, SIRT inhibitor and p53 activator
- Tenovin-6, >=98%
- 4-(tert-Butyl)-N-((4-(4-(dimethylamino)butanamido)phenyl)carbAmothioyl)benzamide
- CAS:
- 1011557-82-6
- MF:
- C25H34N4O2S
- MW:
- 454.63
- EINECS:
- 200-256-5
- Product Categories:
-
- Inhibitors
- Mol File:
- 1011557-82-6.mol
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Tenovin-6 Chemical Properties
- Density
- 1.171±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20° C
- solubility
- ≥22.75 mg/mL in DMSO; insoluble in H2O; ≥2.62 mg/mL in EtOH with ultrasonic
- form
- solid
- pka
- 9.11±0.70(Predicted)
- color
- White to off-white
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Tenovin-6 Usage And Synthesis
Uses
Tenovin-6 Hydrochloride, is a small molecule activator of p53 transcriptional activity. It acts as a potent SIRT1 and SIRT2 inhibitor as well.
Definition
ChEBI: Tenovin-6 is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-(dimethylamino)pentanoic acid with the aromatic amino group of N-[(4-aminophenyl)carbamothioyl]-4-tert-butylbenzamide. It has a role as an antineoplastic agent, a Sir2 inhibitor and a p53 activator. It is a monocarboxylic acid amide, a member of thioureas and a tertiary amino compound.
target
SIRT1
Tenovin-6Supplier
Dalian Meilun Biotech Co., Ltd.
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