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Protoaescigenin

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Protoaescigenin Basic information

Product Name:
Protoaescigenin
Synonyms:
  • Protoaescigenin
  • Protoescigenin
  • (3beta,4beta,16bta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol
  • Protoescigenine
  • Olean-12-ene-3,16,21,22,23,28-hexol, (3β,4β,16α,21β,22α)-
  • (3R,4R,4aR,5R,6aS,6bR,8aR,9S,10S,12aR,12bR,14bS)-4a,9-Bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-3,4,5,10-tetraol
  • Protoescigenin, 10 mM in DMSO
CAS:
20853-07-0
MF:
C30H50O6
MW:
506.71
Mol File:
20853-07-0.mol
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Protoaescigenin Chemical Properties

Density 
1.23±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C
form 
Solid
color 
White to off-white
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Protoaescigenin Usage And Synthesis

Uses

Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene[1].

References

[1] Jatczak, K., et al. Preparation of selectively protected protoescigenin derivatives for synthesis of escin analogs and neoglycoconjugates. cent.eur.j.chem. 12, 1222–1231 (2014).

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