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(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

Basic information Safety Supplier Related

(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Basic information

Product Name:
(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Synonyms:
  • (6R,12aR)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
  • (6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
  • DesMethylene Tadalafil
  • Tadalafil IMpurity: IMpurity I
  • Tadalafil IMpurity K
  • Tadalafil Desmethylene Impurity
  • Tadalafil Catechol
  • (6R,12aR)-6-(3,4-Dihydroxyphenyl)-2-methyl-2,3,6,7,12,12a-hexahydro pyrazino [1′,2′:1,6]-pyrido[3,4-b]indole-1,4-dione
CAS:
171489-03-5
MF:
C21H19N3O4
MW:
377.39
Product Categories:
  • Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
171489-03-5.mol
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(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Chemical Properties

Melting point:
>215°C (dec.)
Boiling point:
735.3±60.0 °C(Predicted)
Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Sparingly), Methanol (Slightly)
pka
9.58±0.10(Predicted)
form 
Solid
color 
Off-White to Light Pink
Stability:
Hygroscopic
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(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Usage And Synthesis

Chemical Properties

Off-White to Pale Pink Solid

Uses

Tadalafil. A phosphodiesterase 5 inhibitor.

(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dioneSupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
Shanghai TaoSu Biochemical Technology Co., Ltd.
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021-33632979
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info@tsbiochem.com
ChemStrong Scientific Co.,Ltd
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0755-66853366 13670046396
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sales@chem-strong.com
Shanghai Kewel Chemical Co., Ltd.
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021-64609169 18901607656
Email
greensnown@163.com
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(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione(171489-03-5)Related Product Information