ChemicalBook > Product Catalog > Organic Chemistry > Heterocyclic Compounds > 2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile
2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile
2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile Basic information
- Product Name:
- 2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile
- Synonyms:
-
- 2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile
- 2-Benzothiazoleacetonitrile, α-(2-chloro-4-pyrimidinyl)-
- JNK-IN-13
- CAS:
- 345986-38-1
- MF:
- C13H7ClN4S
- MW:
- 286.74
- Mol File:
- 345986-38-1.mol
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2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile Chemical Properties
- form
- Solid
- color
- White to yellow
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2-(benzo[d]thiazol-2-yl)-2-(2-chloropyriMidin-4-yl)acetonitrile Usage And Synthesis
Uses
JNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively[1].
IC 50
JNK2: 500 nM (IC50); JNK3: 290 nM (IC50)
References
[1] Serge Halazy, et al. Benzazole derivatives and their use as JNK modulators. EP1110957A1.
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