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24R-Calcipotriol

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24R-Calcipotriol Basic information

Product Name:
24R-Calcipotriol
Synonyms:
  • 24R-Calcipotriol
  • IMpurity D of Calcipotriol
  • PRI 2202
  • (24R)-Calcipotriene
  • (1alpha,3beta,5Z,7E,22E,24R)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol
  • Impurity D of Calcipotriol (PRI 2202)
  • 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4R)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
  • Calcipotriol impurity D
CAS:
112827-99-3
MF:
C27H40O3
MW:
412.6
Product Categories:
  • Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
112827-99-3.mol
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24R-Calcipotriol Chemical Properties

Boiling point:
582.0±50.0 °C(Predicted)
Density 
1.12±0.1 g/cm3(Predicted)
storage temp. 
-20°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
14.29±0.20(Predicted)
form 
Powder
Stability:
Light sensitive, Temperature sensitive
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24R-Calcipotriol Usage And Synthesis

Uses

(24R)-Calcipotriene is a synthetic analogs of vitamin D that was studied for its potential antitumor effects. Studies has shown the combined treatment with vitamin D analog (24R)-Calcipotriene was more effective than the treatment with cytostatics applied alone. (24R)-Calcipotriene is also the 24-R epimer of Calcipotriene (C144200).

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