Corylifol C Chemical Properties

Boiling point:

601.5±55.0 °C(Predicted)

Density 

1.351±0.06 g/cm3(Predicted)

pka

7.56±0.40(Predicted)

Corylifol C Usage And Synthesis

Uses

Corylifol C is a potent protein kinase inhibitor with IC50 valueS of 8.7, 3.0, 2.1, 6.4, 4.5, 6.2, 2.3, 1.2, 5.1 μg/ml for ARK5, Aurora-A, Aurora-B, AXL, B-RAF-VE, CDK4/CycD1, TIE2, EGF-R, EPHB4, respectively[1].

References

[1] Limper C, et al. Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells. J Pharm Pharmacol. 2013 Sep;65(9):1393-408. DOI:10.1111/jphp.12107

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