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Platycodin D2

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Platycodin D2 Basic information

Product Name:
Platycodin D2
Synonyms:
  • Platycodin D2
  • Olean-12-en-28-oic acid, 3-[(3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-2,16,23,24-tetrahydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,16α)-
  • inhibit,Platycodin D2,Platycodin D 2,Inhibitor,Platycodin D-2
CAS:
66663-90-9
MF:
C63H102O33
MW:
1387.46
Mol File:
66663-90-9.mol
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Platycodin D2 Chemical Properties

Density 
1.60±0.1 g/cm3 (20 ºC 760 Torr)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
12.70±0.70(Predicted)
color 
Off-white to light yellow
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Platycodin D2 Usage And Synthesis

Description

Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses. Polygalacin D2 has anti-cancer activity, it exhibits significant inhibition on the proliferation of five kinds of cultured human tumor cell lines.

Definition

ChEBI: Platycodin D2 is a triterpenoid saponin. It has a role as a metabolite.

Biological Activity

Platycodin D2 is a saponin isolated from Platycodon grandiflorum, with anti-cancer activity.

in vitro

A novel triterpenoid saponin, deapioplatycoside Ewas isolated from the root extract of Platycodon grandiflorum, together with the seven known saponins 2 - 8, i. e., platycoside E, deapioplatycodin D3 , platycodin D3, polygalacin D2, Platycodin D2 , deapioplatycodin D and platycodin D. The structure of the new saponin 1 was determined on the basis of spectral analysis and chemical evidence.

target

IFN-γ | IL Receptor | HBV

Platycodin D2Supplier

Chengdu Biopurify Phytochemicals Ltd.
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