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Piperlotine D

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Piperlotine D Basic information

Product Name:
Piperlotine D
Synonyms:
  • N-(3,4,5-trimethoxy-Z-cinnamoyl)pyrrolidine
  • Piperlotine D
  • (2Z)-1-(1-Pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one
  • 2-Propen-1-one, 1-(1-pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-, (2Z)-
CAS:
958296-13-4
MF:
C16H21NO4
MW:
291.34
Mol File:
958296-13-4.mol
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Piperlotine D Chemical Properties

Boiling point:
482.8±45.0 °C(Predicted)
Density 
1.156±0.06 g/cm3(Predicted)
pka
-0.94±0.20(Predicted)
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Piperlotine D Usage And Synthesis

Uses

Piperlotine D is an antiplatelet aggregation agent. Piperlotine D can be extracted from Piper lolot with antiplatelet aggregation activity. Piperlotine D inhibits arachidonic acid-induced platelet aggregation with an IC50 of 43.4 μg/mL[1].

References

[1] Li CY, et al. Isolation and identification of antiplatelet aggregatory principles from the leaves of Piper lolot. J Agric Food Chem. 2007 Nov 14;55(23):9436-42. DOI:10.1016/s0031-9422(03)00422-9

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