Enocitabine Chemical Properties

Melting point:

141-142°C

alpha 

D +70° (c = 1 in THF, 22°)

Boiling point:

630.87°C (rough estimate)

Density 

1.0967 (rough estimate)

refractive index 

1.7800 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Store in freezer, under -20°C

solubility 

DMSO (Slightly, Heated), Methanol (Slightly, Heated), THF (Slightly, Heated, Soncited)

pka

10.14±0.20(Predicted)

form 

Solid

color 

White to Off-White

CAS DataBase Reference

55726-47-1(CAS DataBase Reference)

MSDS

• Language:English Provider:Enocitabine

Enocitabine Usage And Synthesis

Description

Enocitabine (NSC-239336, BHAC) is an antileukemic agent closely related to cytarabine. It appears more resistant to deamination than cytarabine, thus allowing greater in vivo phosphorylation into an active cytotoxic metabolite. Enocitabine is lipophilic, but the drug does not enter the cerebrospinal fluid and is concentrated in the bone marrow and red blood cells. It can be administered orally and appears to be more effective than the parent compound in preclinical models.

Chemical Properties

Crystalline Solid

Originator

Asahi (Japan)

Uses

An antineoplastic. A derivative of Cytarabine.

Definition

ChEBI: Enocitabine is an organic molecular entity.

brand name

SUNRABIN

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