Hedycoronen A
Hedycoronen A Basic information
- Product Name:
- Hedycoronen A
- Synonyms:
-
- Hedycoronen A
- 15-Methoxylabda-8(17),11E,13-trien-16,15-olide
- 2(5H)-Furanone, 3-[(1E)-2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethenyl]-5-methoxy-
- CAS:
- 1383441-73-3
- MF:
- C21H30O3
- MW:
- 330.46
- Mol File:
- 1383441-73-3.mol
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Hedycoronen A Chemical Properties
- Boiling point:
- 458.2±45.0 °C(Predicted)
- Density
- 1.06±0.1 g/cm3(Predicted)
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Hedycoronen A Usage And Synthesis
Uses
Hedycoronen A has inhibitory activity on the IL-6, IL-12 p40, and TNF-α production in LPS-Stimulated BMDCs, with IC50s of 9.1 μM, 5.6 μM, and 46.0 μM. Hedycoronen A can be isolated from Hedychium coronarium[1].
References
[1] Kiem PV, et al. Labdane-type diterpenoids from the rhizomes of Hedychium coronarium inhibit lipopolysaccharide-stimulated production of pro-inflammatory cytokines in bone marrow-derived dendritic cells. Chem Pharm Bull (Tokyo). 2012;60(2):246-50. DOI:10.1248/cpb.60.246
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