Afatinib iMpurity Chemical Properties

Melting point:

>134°C (dec.)

Boiling point:

676.9±55.0 °C(Predicted)

Density 

1.380±0.06 g/cm3(Predicted)

storage temp. 

Amber Vial, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

11.79±0.43(Predicted)

color 

Pale Yellow to Light Yellow

Stability:

Light Sensitive

Afatinib iMpurity Usage And Synthesis

Uses

(2Z)-Afatinib is a structural analogue of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

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