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1-[(2S)-3-BroMo-2-Methyl-1-oxopropyl]-L-proline

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1-[(2S)-3-BroMo-2-Methyl-1-oxopropyl]-L-proline Basic information

Product Name:
1-[(2S)-3-BroMo-2-Methyl-1-oxopropyl]-L-proline
Synonyms:
  • 1-[(2S)-3-BroMo-2-Methyl-1-oxopropyl]-L-proline
  • (2S)-1-[(2S)-3-Bromo-2-methylpropanoyl]pyrrolidine-2-carboxylic acid
  • Captopril impurity B
  • (S)-1-((S)-3-bromo-2-methylpropanoyl)pyrrolidine-2-carboxylic acid
  • Captopril Impurity 2(Captopril EP Impurity B)
  • 1-(3-bromo-2S-methylpropionyl)-pyrrolidine-2S-carboxylic acid
  • L-Proline, 1-(3-bromo-2-methyl-1-oxopropyl)-, (S)-
  • captopril-ep-imp-B
CAS:
80629-35-2
MF:
C9H14BrNO3
MW:
264.12
Product Categories:
  • Inhibitors, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
80629-35-2.mol
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1-[(2S)-3-BroMo-2-Methyl-1-oxopropyl]-L-proline Chemical Properties

Melting point:
110-114℃
Boiling point:
425.1±40.0 °C(Predicted)
Density 
1.555±0.06 g/cm3(Predicted)
pka
3.52±0.20(Predicted)
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1-[(2S)-3-BroMo-2-Methyl-1-oxopropyl]-L-proline Usage And Synthesis

Uses

1-[(2S)-3-Bromo-2-methyl-1-oxopropyl]-L-proline is an intermediate in the synthetic preparation of Captopril (C175750), a orally active angiotensin-converting enzyme (ACE) inhibitor.

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