2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid Chemical Properties

Melting point:

225-228°C

Boiling point:

538.9±60.0 °C(Predicted)

Density 

1.291±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

1.22±0.37(Predicted)

color 

White to Off-White

2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid Usage And Synthesis

Uses

2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid is an impurity of Febuxostat (F229000), an xanthine oxidase/xanthine dehydrogenase inhibitor used for the treatment of hyperuricemia and chronic gout.

2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid(1239233-86-3)Related Product Information

• Febuxostat
• ethyl 2-(3-hydroxyphenyl)-4-methylthiazole-5-Carboxylate
• Febuxostat Impurity 46
• 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid
• 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid
• 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid
• Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
• 4-Hydroxyisophthalonitrile
• 4-HYDROXYTHIOBENZAMIDE
• Febuxostat Acyl-β-D-glucuronide
• 4-(2-Methylpropoxy)-1,3-benzenedicarbonitrile
• ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
• ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE
• Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate
• Febuxostat Descyano Impurity
• isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
• ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
• 3-Cyano-4-isobutoxybenzoic acid