2-[3-Carboxy-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid Chemical Properties

Melting point:

218-222°C

Boiling point:

568.9±60.0 °C(Predicted)

Density 

1.327±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

1.21±0.37(Predicted)

form 

Solid

color 

White to Off-White

2-[3-Carboxy-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid Usage And Synthesis

Uses

2-[3-Carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid is an impurity of Febuxostat (F229000), an xanthine oxidase/ xanthine dehydrogenase inhibitor used for the treatment of hyperuricemia and chronic gout.

2-[3-Carboxy-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid(1239233-87-4)Related Product Information

• Febuxostat Acyl-β-D-glucuronide
• Febuxostat Descyano Impurity
• isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
• 2-(2-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid ethyl ester
• Febuxostat Impurity 7
• 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 5,5'-DiMethyl Ester
• Febuxostat Impurity 14
• 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
• Febuxostat Impurity 6
• 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid
• 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid
• Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
• ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
• ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE
• 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide
• 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID
• FeBuxostat Impurity 18
• 4-HYDROXYTHIOBENZAMIDE