Basic information Safety Supplier Related

4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid

Basic information Safety Supplier Related

4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Basic information

Product Name:
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid
Synonyms:
  • Indapamide EP Impurity F
  • Indomethacin EP Impurity F
  • Indometacin Impurity 14
  • Indomethacin Impurity 6(Indomethacin EP Impurity F)
  • Indometacin EP Impurity F
  • Indomethacin Impurity F
  • Indometacin (Indomethacin) EP Impurity F
  • Indomethacin impurity 5/Indomethacin EP Impurity F/2-(4-Chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide-4-chloro-benzoic acid
CAS:
402849-27-8
MF:
C21H16Cl2N2O3
MW:
415.27
Product Categories:
  • Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
402849-27-8.mol
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4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Chemical Properties

Melting point:
159-163°C
Density 
1.370±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Soncited)
form 
Solid
pka
9.41±0.46(Predicted)
color 
White to Pale Beige
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4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Usage And Synthesis

Uses

4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid is an impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.

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