4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Basic information
- Product Name:
- 4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid
- Synonyms:
-
- Indapamide EP Impurity F
- Indomethacin EP Impurity F
- Indometacin Impurity 14
- Indomethacin Impurity 6(Indomethacin EP Impurity F)
- Indometacin EP Impurity F
- Indomethacin Impurity F
- Indometacin (Indomethacin) EP Impurity F
- Indomethacin impurity 5/Indomethacin EP Impurity F/2-(4-Chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide-4-chloro-benzoic acid
- CAS:
- 402849-27-8
- MF:
- C21H16Cl2N2O3
- MW:
- 415.27
- Product Categories:
-
- Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File:
- 402849-27-8.mol
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4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Chemical Properties
- Melting point:
- 159-163°C
- Density
- 1.370±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Soncited)
- form
- Solid
- pka
- 9.41±0.46(Predicted)
- color
- White to Pale Beige
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4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Usage And Synthesis
Uses
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid is an impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.
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4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid(402849-27-8)Related Product Information
- Indometacin Impurity 16
- 4-Chloro-N-(4-Methoxyphenyl)benzaMide, 97%
- IndoMethacin DiaMide
- Indometacin EP Impurity G
- Benzoic acid, 4-chloro-, 2,3-dihydroxypropyl ester
- 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-hydroxypropyl ester
- Indometacin Impurity 15
- Indometacin Impurity 18
- Methanone, (4-chlorophenyl)[2,6-dichloro-4-(hydroxymethyl)phenyl]-
- Indometacin Impurity 17
- Indometacin EP Impurity D
- 2-(4-METHOXYPHENYL)HYDRAZINESULFONIC ACID SODIUM SALT MONOHYDRATE
- 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID
- 4-Chlorobenzoic acid
- 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester
- Indometacin
- methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
- Indomethacin-d4