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Dasatinib DiMeric IMpurity

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Dasatinib DiMeric IMpurity Basic information

Product Name:
Dasatinib DiMeric IMpurity
Synonyms:
  • Dasatinib Impurity 8 (Dasatinib Dimeric Impurity)
  • 2,2'-[1,4-Piperazinediylbis[(2-methyl-6,4-pyrimidinediyl)imino]]bis[N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide
  • Dasatinib Dimer Impurity
  • Dasatinib impurity 6/Dasatinib Dimeric Impurity/2,2'-((piperazine-1,4-diylbis(2-methylpyrimidine-6,4-diyl))bis(azanediyl))bis(N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide)
  • dasatinib Dimer IMP
  • N-(2-chloro-6-methylphenyl)
  • 5-Thiazolecarboxamide, 2,2'-[1,4-piperazinediylbis[(2-methyl-6,4-pyrimidinediyl)imino]]bis[N-(2-chloro-6-methylphenyl)- (9CI)
  • Dasatinib monohydrate D
CAS:
910297-61-9
MF:
C36H34Cl2N12O2S2
MW:
801.77
Product Categories:
  • Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors
Mol File:
910297-61-9.mol
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Dasatinib DiMeric IMpurity Chemical Properties

Density 
1.501±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Very Slightly)
form 
Solid
pka
10?+-.0.70(Predicted)
color 
Off-White to Dark Beige
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Dasatinib DiMeric IMpurity Usage And Synthesis

Uses

Dasatinib Dimeric Impurity, is an impurity of Dasatinib (D193600), which is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. It is also an Antineoplastic. It is a COVID19-related research product.

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