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Methotrexate α-Methyl Ester

Basic information Safety Supplier Related

Methotrexate α-Methyl Ester Basic information

Product Name:
Methotrexate α-Methyl Ester
Synonyms:
  • JYFDQHNTJJOKAS-AWEZNQCLSA-N
  • Methotrexate EP Impurity I
  • Methotrexate Impurity 9(EP-I)
  • Methotrexate α-Methyl Ester (Impurity I)
  • Methotrexate EP Impurity I(Amethopterin EP Impurity I)
  • (4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
  • Methotrexate EP Impurity I/Methotrexate 1-Methyl Ester/Methotrexate α-Methyl Ester/(4S)-4-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
  • Methotrexate EP Impurity I (Methotrexate-1-Monomethyl Ester)
CAS:
66147-29-3
MF:
C21H24N8O5
MW:
468.47
Product Categories:
  • Aromatics, Chiral Reagents, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
66147-29-3.mol
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Methotrexate α-Methyl Ester Chemical Properties

solubility 
Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
color 
Light Yellow to Dark Orange
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Methotrexate α-Methyl Ester Usage And Synthesis

Uses

Methotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

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