Basic information Safety Supplier Related

(R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

Basic information Safety Supplier Related

(R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Basic information

Product Name:
(R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
Synonyms:
  • (R)-Apremilast
  • Apremilast R-Isomer
  • Apremilast Impurity 5(R-Isomer)
  • (R)-CC-10004
  • (R)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylamino isoindoline-1,3-dione
  • Acetamide, N-[2-[(1R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
  • (R)-Apremilast ((R)-CC10004)
  • Apremilast Impurity(R-Isomer) 30
CAS:
608141-44-2
MF:
C22H24N2O7S
MW:
460.5
Mol File:
608141-44-2.mol
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(R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Chemical Properties

Melting point:
>75°C (dec.)
Boiling point:
741.3±60.0 °C(Predicted)
Density 
1.381±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
14.01±0.20(Predicted)
form 
Solid
color 
Pale Yellow to Pale Green
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(R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Usage And Synthesis

Uses

(R)-Apremilast is an enantiomer of Apremilast (A729700), an oral phosphodiesterase 4 inhibitor is used in the treatment of psoriatic arthritis.

(R)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamideSupplier

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