Basic information Safety Supplier Related

Entacapone EP Impurity G

Basic information Safety Supplier Related

Entacapone EP Impurity G Basic information

Product Name:
Entacapone EP Impurity G
Synonyms:
  • Entacapone EP Impurity G
  • N,N-Bis-desethyl, N-Methyl Entacapone
  • 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methyl-, (2E)-
  • (E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylacrylamide (Entacapone Impurity)
CAS:
1364322-41-7
MF:
C11H9N3O5
MW:
263.21
Mol File:
1364322-41-7.mol
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Entacapone EP Impurity G Chemical Properties

Boiling point:
544.6±50.0 °C(Predicted)
Density 
1.537±0.06 g/cm3(Predicted)
pka
4.88±0.50(Predicted)
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Entacapone EP Impurity G Usage And Synthesis

Uses

N,N-Bis-desethyl, N-Methyl Entacapone is an impurity of Entacapone (E558500). The (E)-Isomer of Entacapone which is a polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.

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