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(S)-4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine

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(S)-4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine Basic information

Product Name:
(S)-4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine
Synonyms:
  • (S)-4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine
  • Lusutrombopag intermediate
  • (S)-4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine(WXG02539)
  • 4-(3-((S)-1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine
  • A241SM1
  • Lusutrombopag ITS-1 (S)-4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine
  • 2-Thiazolamine, 4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-
  • Lusutrombopag Impurity 7
CAS:
1110767-98-0
MF:
C18H26N2O2S
MW:
334.48
Mol File:
1110767-98-0.mol
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(S)-4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine Chemical Properties

Boiling point:
462.4±45.0 °C(Predicted)
Density 
1.105±0.06 g/cm3(Predicted)
pka
4.30±0.10(Predicted)
InChI
InChI=1S/C18H26N2O2S/c1-4-5-6-7-11-22-13(2)14-9-8-10-15(17(14)21-3)16-12-23-18(19)20-16/h8-10,12-13H,4-7,11H2,1-3H3,(H2,19,20)/t13-/m0/s1
InChIKey
VTLKOIONKYXPQL-ZDUSSCGKSA-N
SMILES
S1C=C(C2=CC=CC([C@@H](OCCCCCC)C)=C2OC)N=C1N
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(S)-4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-amine Usage And Synthesis

Uses

(S)?-?4-?(3-?(1-?(Hexyloxy)?ethyl)?-?2-?methoxyphenyl)?thiazol-?2-?amine is an intermediate of Lusutrombopag (L474985), a newly discovered thrombopoietin receptor agonist used in the treatment of patients with chronic ITP.

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