Basic information Safety Supplier Related

DL-DECANOYLCARNITINE CHLORIDE

Basic information Safety Supplier Related

DL-DECANOYLCARNITINE CHLORIDE Basic information

Product Name:
DL-DECANOYLCARNITINE CHLORIDE
Synonyms:
  • (+/-)-DECANOYLCARNITINE CHLORIDE
  • DL-DECANOYLCARNITINE CHLORIDE
  • Decanoyl-L-carnitine chloride≥ 98% (TLC)
  • (+/-)-Decanoylcarnitinechloride
  • (+/-)-Decanoylcarnit
CAS:
14919-36-9
MF:
C17H34ClNO4
MW:
351.91
Product Categories:
  • Lipid signaling
Mol File:
14919-36-9.mol
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DL-DECANOYLCARNITINE CHLORIDE Chemical Properties

storage temp. 
−20°C
solubility 
<35.19mg/ml in H2O
form 
solid
color 
White
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Safety Information

WGK Germany 
3

MSDS

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DL-DECANOYLCARNITINE CHLORIDE Usage And Synthesis

Chemical Properties

White crystalline powder

Biological Activity

(±)-decanoylcarnitine chloride is an agonist for cholinergic and a homolog of acetylcarnitine chloride (cat no. b6273).acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-decanoylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3].

DL-DECANOYLCARNITINE CHLORIDESupplier

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