Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  fatty acid >  DL-Mandelic acid

DL-Mandelic acid

Basic information Safety Supplier Related

DL-Mandelic acid Basic information

Product Name:
DL-Mandelic acid
Synonyms:
  • (n)-mandelic acid
  • DL-MANDELIC ACID611-72-3
  • MANDELICACIDANDITSCOMMONSALTS
  • alpha-Hydroxy-benzeneacetic acid
  • alpha-Hydroxyphenylacetic acid
  • Kyselina 2-fenyl-2-hydroxyethanova
  • Kyselina mandlova
  • kyselina2-fenyl-2-hydroxyethanova
CAS:
90-64-2
MF:
C8H8O3
MW:
152.15
EINECS:
202-007-6
Product Categories:
  • Pharmaceutical intermediates
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acids
  • Chemical Synthesis
  • Organic Building Blocks
  • C8
  • Carbonyl Compounds
  • Carboxylic Acids
  • Pyridines ,Halogenated Heterocycles
  • 90-64-2
Mol File:
90-64-2.mol
More
Less

DL-Mandelic acid Chemical Properties

Melting point:
119-121 °C (lit.)
Boiling point:
214.6°C (rough estimate)
alpha 
[α]D20 -0.5~+0.5° (c=2, H2O)
Density 
1.30
vapor pressure 
0.01 Pa (50 °C)
refractive index 
1.4810 (estimate)
storage temp. 
Store below +30°C.
solubility 
139g/l
form 
Crystals or Crystalline Powder
pka
3.85(at 25℃)
color 
White
PH
2.3 (10g/l, H2O)
Odor
faint odor
optical activity
[α]/D 0±1°, c = 5 in H2O
Water Solubility 
150 g/L (20 ºC)
Sensitive 
Light Sensitive
Merck 
14,5717
BRN 
510011
InChIKey
IWYDHOAUDWTVEP-UHFFFAOYSA-N
LogP
0.5 at 23℃
CAS DataBase Reference
90-64-2(CAS DataBase Reference)
NIST Chemistry Reference
Benzeneacetic acid, «alpha»-hydroxy-(90-64-2)
EPA Substance Registry System
Mandelic acid (90-64-2)
More
Less

Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-22
Safety Statements 
22-24/25-37/39-26-36
WGK Germany 
3
RTECS 
OO6300000
TSCA 
Yes
HS Code 
29181990

MSDS

More
Less

DL-Mandelic acid Usage And Synthesis

Chemical Properties

White rhomboidal crystals, decompose when exposed to light. Soluble in ether and isopropanol, soluble in ethanol and water; R-form melting point is 133°C, [α]-159.73° (ethanol), gradually racemic at 160°C. S-form melting point is 133.8°C, [α]+156.57° (water).

Uses

Organic synthesis, medicine (urinary antiseptic).

Uses

DL-Mandelic acid may be used as an analytical reference standard for the determination of DL-mandelic acid in:
Human urine samples by high performance liquid chromatography (HPLC) equipped with ultraviolet (UV) detector.
Rat urine samples by gas chromatography-mass spectrometry (GC-MS) with selected ion monitoring (SIM) detection.

Preparation

Mandelic acid can be prepared by the hydrolysis of amygdalin with sulfuric acid or of mandelonitrile with hydrochloric acid. The mandelonitrile can be prepared by the action of hydrocyanic acid on benzaldehyde, and by the action of sodium or potassium cyanide on the sodium bisulfite addition product of benzaldehyde. The procedure described differs from earlier methods in that the sodium bisulfite addition compound of benzaldehyde is prepared in the presence of sodium cyanide and the nitrile is formed immediately.
synthesis of mandelic acid

Definition

ChEBI: Mandelic acid is a 2-hydroxy monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by phenyl and hydroxyl groups. It has a role as an antibacterial agent and a human xenobiotic metabolite. It is a 2-hydroxy monocarboxylic acid and a member of benzenes. It derives from an acetic acid. It is a conjugate acid of a mandelate. Exists in stereoisomeric forms. The properties are those of the dl-form.

General Description

DL-Mandelic acid is an aromatic hydrocarbon metabolite of styrene.

Hazard

Toxic by ingestion.

Flammability and Explosibility

Not classified

Safety Profile

Poison by intramuscular route. Moderately toxic by ingestion. Continued absorption can cause kidney irritation. When heated to decomposition it emits acrid smoke and irritating fumes.

DL-Mandelic acid Supplier

Spec-Chem Industry Inc. Gold
Tel
13505162978
Email
sc@specchemind.com
Hubei Keyijia Chemical Co., Ltd. Gold
Tel
15629167229
Email
1796273473@qq.com
Xi'an Bright Herb Biotech Co., Ltd. Gold
Tel
17391987094 18729593924
Email
1273976566@qq.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com