Xanthone Chemical Properties

Melting point:

172-174 °C(lit.)

Boiling point:

349-350 °C730 mm Hg(lit.)

Density 

1.1607 (rough estimate)

refractive index 

1.6000 (estimate)

Flash point:

350-351°C

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly, Heated)

form 

Solid

color 

White to Light Purple

Water Solubility 

It is Soluble in water (partly), chloroform, hot Toluene, ether (slightly), and hot alcohol.

Merck 

14,10062

BRN 

140443

Stability:

Stable. Incompatible with strong oxidizing agents.

InChIKey

JNELGWHKGNBSMD-UHFFFAOYSA-N

CAS DataBase Reference

90-47-1(CAS DataBase Reference)

NIST Chemistry Reference

Xanthone(90-47-1)

EPA Substance Registry System

9H-Xanthen-9-one (90-47-1)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22

Safety Statements 

24/25-62-45

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

ZD5711000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29329990

MSDS

• Language:English Provider:9-Xanthenone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Xanthone Usage And Synthesis

Description

Xanthone is a compound that has been shown to have a significant cytotoxicity against HL-60 cells and to inhibit the cyclase enzyme. It also inhibits the protein production of mcl-1, which is necessary for the development of cancer cells.

Chemical Properties

off-white powder

Uses

Acts as an inhibitor of human cancer cell lines.

Uses

Xanthone is used predominantly as oxygenated polycyclic aromatic compounds, and as a vasorelaxant. It can be used as a fluorescent agent, as well as an intermediate in organic synthesis and chemical research.

Definition

ChEBI: The parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9.

Application

Xanthone has antiinflammatory activity and can be used in treating infectious diseases such as tuberculosis, malaria, and leprosy. The biological properties of it are shown by its ability to scavenge anion radicals and to act as a fluorescence probe for coumarin derivatives.

Definition

A colorless crystalline organic compound found as a pigment in gentians and other flowers. It is used as an insecticide and in making dyestuffs.

Synthesis Reference(s)

The Journal of Organic Chemistry, 37, p. 4204, 1972 DOI: 10.1021/jo00798a059

Purification Methods

It has also been recrystallised from n-hexane three times and sublimed in vacuo. [Saltiel J Am Chem Soc 108 2674 1986]. [Beilstein 17 H 354, 17 I 190, 17 II 378, 17 III/IV 5292, 17/10 V 430.]

Xanthone(90-47-1)Related Product Information

• 2-Isopropylthioxanthone
• XANTHONE-C-GLUCOSIDE, FROM MANGIFERA INDICA LEAVES,XANTHONE-C-GLUCOSIDE
• GENTISIN
• isomangiferin
• STERIGMATOCYSTIN
• 1,3,6-TRIHYDROXY-7-METHOXY-2,8-DI(3-METHYL-2-BUTENYL)XANTHONE,1,3,6-Trihydroxy-7-methoxy-2,8-bis(3,3-dimethylallyl)xanthone
• 2,4-Diethyl-9H-thioxanthen-9-one
• 1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-butenyl)xanthone
• XANTHONE(RG)
• Xanthene
• Anthrone
• isogentisin
• 1-HYDROXY-3,7-DIMETHOXYXANTHONE
• MACLURAXANTHONE
• 9H-Xanthen-9-one, 1,3,7-trimethoxy-
• GENTISEIN
• 3,6-Dimethoxyxanthone
• 2-(TRIFLUOROMETHYL)XANTHONE,2-(TRIFLUOROMETHYL)XANTHONE 97%