Basic information Safety Supplier Related

Benzyl-PEG7-amino

Basic information Safety Supplier Related

Benzyl-PEG7-amino Basic information

Product Name:
Benzyl-PEG7-amino
Synonyms:
  • Benzyl-PEG7-amino
  • Benzyl-PEG6-amino
  • Benzyl-PEG6-amine
  • Benzyl-PEG7-amine
  • BnO-PEG6-CH2CH2NH2
  • CAS_868594-43-8
  • 3,6,9,12,15,18,21-Heptaoxadocosan-1-amine, 22-phenyl-
  • Benzyl-PEG7-NH2
CAS:
868594-43-8
MF:
C21H37NO7
MW:
415.52
Mol File:
868594-43-8.mol
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Benzyl-PEG7-amino Usage And Synthesis

Biological Activity

Benzyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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