Cyanine5 NHS ester Chemical Properties

solubility 

Soluble in organic solvents such as DMF

Appearance

Dark blue solid

ex/em

640/664nm (PBS buffer)

ε(extinction coefficient)

250000 L⋅mol−1⋅cm−1

Φ(quantum yield)

0.2

InChIKey

WYDRTLYIBJFWFL-UHFFFAOYSA-M

SMILES

C([N+]1=C(C(C)(C)C2=CC=CC=C12)C=CC=CC=C1C(C2=CC=CC=C2N1C)(C)C)CCCCC(=O)ON1C(CCC1=O)=O.[Cl-]

Safety Information

HS Code 

32049010

Cyanine5 NHS ester Usage And Synthesis

Chemical Properties

Appearance: Dark blue solid
ex/em: 640/664nm (PBS buffer)
Extinction coefficient (ε): 250000 L??mol??1??cm??1
Quantum yield (Φ): 0.2

Uses

Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides[1].

References

[1] Brugada-Vilà P, et al. Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses. Theranostics. 2020;10(6):2744-2758. DOI:10.7150/thno.40902

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