DE-7 Chemical Properties

Melting point:

72-73 °C

Boiling point:

393.9±38.0 °C(Predicted)

Density 

1.68±0.1 g/cm3(Predicted)

solubility 

Chloroform, DCM

form 

Solid

pka

-2.55±0.60(Predicted)

color 

Off-White

DE-7 Usage And Synthesis

Uses

2-Chloro-1-[[(2R)-2-methyloxiranyl]methyl]-4-nitro-1H-imidazole is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.