4-Phenylmorpholine Chemical Properties

Melting point:

51-54 °C(lit.)

Boiling point:

165-170 °C45 mm Hg(lit.)

Density 

1.053 g/cm3 (60℃)

vapor density 

5.63 (vs air)

vapor pressure 

<0.1 mm Hg ( 20 °C)

refractive index 

1.5400 (estimate)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

solubility 

3.46 g/L

pka

5.19±0.40(Predicted)

form 

powder to crystal

color 

White to Light yellow to Light red

Water Solubility 

3.46 g/L

InChIKey

FHQRDEDZJIFJAL-UHFFFAOYSA-N

LogP

1.360 (est)

CAS DataBase Reference

92-53-5(CAS DataBase Reference)

NIST Chemistry Reference

Morpholine, 4-phenyl-(92-53-5)

EPA Substance Registry System

Morpholine, 4-phenyl- (92-53-5)

Safety Information

Hazard Codes 

T

Risk Statements 

22-24

Safety Statements 

36/37-45-36/37/39-28A

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

2

RTECS 

QE8575000

Autoignition Temperature

410 °C

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29349990

Toxicity

LD50 orally in Rabbit: 930 mg/kg LD50 dermal Rabbit 360 mg/kg

MSDS

• Language:English Provider:N-Phenylmorpholine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

4-Phenylmorpholine Usage And Synthesis

Chemical Properties

white to brownish crystalline solid

Uses

4-Phenylmorpholine was used as internal standard during the determination of alkaloids by gas chromatographic method.

Synthesis Reference(s)

The Journal of Organic Chemistry, 50, p. 1365, 1985 DOI: 10.1021/jo00209a004

General Description

4-Phenylmorpholine undergoes oxidation to yield N-formyl-N-2-hydroxyethylaniline.

Safety Profile

Poison by skin contact. Moderately toxic by ingestion. An eye irritant. When heated to decomposition it emits toxic fumes of NOx.

4-Phenylmorpholine(92-53-5)Related Product Information

• Moroxydine
• Dimethomorph
• N-Formylmorpholine
• Moroxydine hydrochloride
• Tridemorph
• 2-Methoxy-4-morpholinobenzenediazonium chloride zinc chloride double salt
• 3-AMINO-4-(4-MORPHOLINO)BENZOTRIFLUORIDE
• 2-MORPHOLINOANILINE
• 2-(4-MORPHOLINO)PHENOL
• 4-MORPHOLINOACETOPHENONE
• 4-MORPHOLINOPHENYL ISOTHIOCYANATE
• 4-(2,5-Diethoxy-4-nitrophenyl)morpholine
• 4-(4-NITROPHENYL)MORPHOLINE
• 3-CHLORO-4-MORPHOLINOANILINE
• 3-MORPHOLINOPHENOL
• 1-(4-Fluorophenyl)piperazine
• 4-Morpholinoaniline
• 4-(2,6-DIMETHYLMORPHOLINO)ANILINE, TECH