N,N'-bis-(propargyl-PEG4)-Cy5 Chemical Properties

solubility 

Soluble in DMSO, DMF, DCM, low solubility in water

N,N'-bis-(propargyl-PEG4)-Cy5 Usage And Synthesis

Description

N,N'-bis-(propargyl-PEG4)-Cy5 is a cyanine linker with excitation/emmission maximum 649/667 nm containing an alkyne group, which enables Click Chemistry to attach deeply colored and photostable Cyanine fluorophore to various molecules.

Uses

N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N,N'-bis-(propargyl-PEG4)-Cy5(2107273-08-3)Related Product Information

• N-(m-PEG4)-N'-(hydroxy-PEG2)-Cy5
• N-(m-PEG4)-N'-(azide-PEG4)-Cy3
• N-(m-PEG4)-N'-(azide-PEG4)-Cy7
• N-PEG3-N'-(azide-PEG3)-Cy5
• N-PEG3-N'-(propargyl-PEG4)-Cy5