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Sofosbuvir metabolites

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Sofosbuvir metabolites Basic information

Product Name:
Sofosbuvir metabolites
Synonyms:
  • ((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl phenyl hydrogen phosphate
  • Sofosbuvir impurity 29/((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl phenyl hydrogen phosphate
  • 5'-Uridylic acid, 2'-deoxy-2'-fluoro-2'-methyl-, monophenyl ester, (2'R)-
  • ((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl phenyl hydrogen phosphate? (sofosbuvir Impurity)
  • Sofosbuvir Impurity SA15434
  • Phenyl Hydrogen (2′R)-2′-Deoxy-2′-fluoro-2′-methyl-5′-uridylate
CAS:
1859162-80-3
MF:
C16H18FN2O8P
MW:
416.29
Mol File:
1859162-80-3.mol
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Sofosbuvir metabolites Chemical Properties

Density 
1.57±0.1 g/cm3(Predicted)
pka
1.25±0.50(Predicted)
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Sofosbuvir metabolites Usage And Synthesis

Uses

Phenyl Hydrogen (2′R)-2′-Deoxy-2′-fluoro-2′-methyl-5′-uridylate can be useful in the development of HPLC method for purity test by design of experiments and determination of activation energy of hydrolytic degrdradation reactions of sofosbuvir.

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