Basic information Safety Supplier Related

Thiourea, N-(2-aminoethyl)-N'-(5-bromo-6-quinoxalinyl)-

Basic information Safety Supplier Related

Thiourea, N-(2-aminoethyl)-N'-(5-bromo-6-quinoxalinyl)- Basic information

Product Name:
Thiourea, N-(2-aminoethyl)-N'-(5-bromo-6-quinoxalinyl)-
Synonyms:
  • Thiourea, N-(2-aminoethyl)-N'-(5-bromo-6-quinoxalinyl)-
  • Brimonidine Impurity 1
  • N-(2-Aminoethyl)-N'-(5-bromo-6-quinoxalinyl)thiourea
  • Brimonidine Impurity 22
  • 1-(2-aminoethyl)-3-(5-bromoquinoxalin-6-yl)thiourea
  • Brimonidine Open Ring Impurity
  • Des-imidazol Impurity
  • Thiourea, N-(2-aminoethyl)-N'-(5-bromo-6-quinoxalinyl)-
CAS:
134892-47-0
MF:
C11H12BrN5S
MW:
326.22
Mol File:
134892-47-0.mol
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Thiourea, N-(2-aminoethyl)-N'-(5-bromo-6-quinoxalinyl)- Chemical Properties

Melting point:
>102°C (dec.)
Boiling point:
466.1±55.0 °C(Predicted)
Density 
1.663±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka
10.86±0.70(Predicted)
form 
Solid
color 
Yellow to Very Dark Yellow
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Thiourea, N-(2-aminoethyl)-N'-(5-bromo-6-quinoxalinyl)- Usage And Synthesis

Uses

N-?(2-?Aminoethyl)?-?N''-?(5-?bromo-?6-?quinoxalinyl)?thiourea is a synthetic impurity in the preparation of Brimonidine (B677520) which is an adrenergic agonist for treatment of glaucoma, diarrhea and kidney disorders.

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