Basic information Safety Supplier Related

[1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis-

Basic information Safety Supplier Related

[1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis- Basic information

Product Name:
[1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis-
Synonyms:
  • [1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis-
  • 3,6,9,12-Tetraoxatetradecane-1,14-dioic Acid
  • HOOCCH2O-PEG3-CH2COOH
  • 3,6,9,12-Tetraoxatetradecanedioic acid
  • COOH-CH2-PEG4-CH2-COOH
  • 4-Isoxazoleaceticacid,3,9-dimethyl-
  • HOOCCH2O-PEG3-CH2COOH/3,6,9,12-Tetraoxatetradecanedioic acid
  • 2-[2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]ethoxy]acetic acid
CAS:
32775-08-9
MW:
266.25
Mol File:
32775-08-9.mol
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[1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis- Chemical Properties

Boiling point:
468.0±35.0 °C(Predicted)
Density 
1.278±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
3.09±0.10(Predicted)
form 
Solid
color 
White to light yellow
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[1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis- Usage And Synthesis

Uses

CH2COOH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

[1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis-Supplier

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