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2,4-Dihydroxypyrimidine-5-carboxylic acid

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2,4-Dihydroxypyrimidine-5-carboxylic acid Basic information

Product Name:
2,4-Dihydroxypyrimidine-5-carboxylic acid
Synonyms:
  • 1,2,3,4-TETRAHYDRO-2,4-DIOXO-5-PYRIMIDINECARBOXYLIC ACID
  • 2,4-DIHYDROXYPYRIMIDINE-5-CARBOXYLIC ACID
  • 5-CARBOXY-2,4-DIHYDROXYPYRIMIDINE
  • 5-CARBOXYURACIL extrapure
  • 2,4-Dioxo-11,2,3,4-tetrahydropyrimidine-5-carboxylic acid
  • 2,4-Dioxo-1H-pyrimidine-5-carboxylic acid
  • 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-
  • 1,2,3,6-Tetrahydro-2,6-dioxo-5-pyrimidinecarboxylic acid
CAS:
23945-44-0
MF:
C5H4N2O4
MW:
156.1
EINECS:
245-947-2
Product Categories:
  • Heterocycle-Pyrimidine series
  • Bases & Related Reagents
  • Carboxylic Acids
  • Nucleotides
  • Carboxylic Acids
  • Pyrazines, Pyrimidines & Pyridazines
  • Pyrazines, Pyrimidines & Pyridazines
  • Pyridine
  • Nucleotides and Nucleosides
Mol File:
23945-44-0.mol
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2,4-Dihydroxypyrimidine-5-carboxylic acid Chemical Properties

Melting point:
283 °C (dec.)(lit.)
Boiling point:
280.29°C (rough estimate)
Density 
1.6814 (rough estimate)
refractive index 
1.4800 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in DMSO
form 
Crystalline Powder
pka
5.08±0.20(Predicted)
color 
White to slightly yellow
Water Solubility 
1.8g/L(20 ºC)
CAS DataBase Reference
23945-44-0(CAS DataBase Reference)
EPA Substance Registry System
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo- (23945-44-0)
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Safety Information

Risk Statements 
36/37/38
Safety Statements 
24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29335990

MSDS

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2,4-Dihydroxypyrimidine-5-carboxylic acid Usage And Synthesis

Chemical Properties

white to slightly yellow crystalline powder or

Uses

2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been used for the visual sensing of melamine (at parts-per-billion (ppb) level) by a highly sensitive analytical method based on Au nanoparticles.

Definition

ChEBI: Uracil-5-carboxylic acid is a pyrimidinemonocarboxylic acid that is uracil carrying a carboxy group at position 5. It is functionally related to a uracil. It is a conjugate acid of a uracil-5-carboxylate. It is a tautomer of a 2,4-dihydroxypyrimidine-5-carboxylic acid.

General Description

2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. It has been used to synthesize N1-alkylated uracil derivatives.

2,4-Dihydroxypyrimidine-5-carboxylic acid Preparation Products And Raw materials

Raw materials

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