PF-5190457
PF-5190457 Basic information
- Product Name:
- PF-5190457
- Synonyms:
-
- PF-5190457
- PF-05190457
- 1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone
- PF-05190457 >=95% (HPLC)
- PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit
- Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-
- (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone
- (R)-2-(2-Methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethan-1-one
- CAS:
- 1334782-79-4
- MF:
- C29H32N6OS
- MW:
- 512.67
- Mol File:
- 1334782-79-4.mol
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PF-5190457 Chemical Properties
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- DMSO: 250 mg/mL (487.64 mM)
- pka
- 8.38±0.20(Predicted)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D +45 to +55°, c = 0.5 in methanol
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PF-5190457 Usage And Synthesis
Uses
PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist.
Biochem/physiol Actions
PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.
storage
Store at -20°C
PF-5190457Supplier
Nanjing Chemlin Chemical Co., Ltd
- Tel
- 025-83697070
- info@chemlin.com.cn
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696,15000506266 15000506266
Shanghai Rechem science Co., Ltd.
- Tel
- 21-31433387 15618786686
- sales@rechemscience.com
Jinan elephant international trading co., LTD
- Tel
- 13006575422@163.com
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PF-5190457(1334782-79-4)Related Product Information
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- PF-04691502
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- PF 477736