Basic information Safety Supplier Related

PF-5190457

Basic information Safety Supplier Related

PF-5190457 Basic information

Product Name:
PF-5190457
Synonyms:
  • PF-5190457
  • PF-05190457
  • 1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone
  • PF-05190457 >=95% (HPLC)
  • PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit
  • Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-
  • (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone
CAS:
1334782-79-4
MF:
C29H32N6OS
MW:
512.67
Mol File:
1334782-79-4.mol
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PF-5190457 Chemical Properties

Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMSO: 250 mg/mL (487.64 mM)
pka
8.38±0.20(Predicted)
form 
powder
color 
white to beige
optical activity
[α]/D +45 to +55°, c = 0.5 in methanol
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PF-5190457 Usage And Synthesis

Uses

PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist.

Biochem/physiol Actions

PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.

storage

Store at -20°C

PF-5190457Supplier

Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Email
info@chemlin.com.cn
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Email
sales@rechemscience.com
Jinan elephant international trading co., LTD
Tel
Email
13006575422@163.com
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PF-5190457(1334782-79-4)Related Product Information