Cyanine7 NHS ester Chemical Properties

solubility 

Soluble in organic solvents such as DMF

Appearance

Dark green solid

ex/em

740/770 nm (MeOH/PBS)

ε(extinction coefficient)

199000 L⋅mol−1⋅cm−1

Φ(quantum yield)

0.3

Cyanine7 NHS ester Usage And Synthesis

Description

Amine reactive Cyanine7, near infrared fluorescent dye, an improved analog of Cy7®.

NIR fluorophores can be used to take advantage of near infrared window of biological tissues - increased transparency of tissues in this spectral region allows to carry out in vivo imaging.

This reagent can be utilized to produce Cyanine7-labeled biomolecules for subsequent use in various in vivo research, and drug design related experiments.

The structure of Cyanine7 features rigidized design of central polymethyne chain. This molecular reinforcement allows to increase quantum yield by 20% compared with parent structure, increasing fluorescence brightness.

This reagent requires organic co-solvent for the labeling (please see Recommended Protocols section below). Water-soluble Cyanine7 NHS ester is also available, and recommended for protein NIR labeling.

Chemical Properties

Appearance: Dark green solid
ex/em: 740/770 nm (MeOH/PBS)
Extinction coefficient (ε): 199000 L??mol??1??cm??1
Quantum yield (Φ): 0.3

Abs/Em Maxima

750/773 nm

Fluoresene quantum yield

0.3

Extinction Coefficient

199000

CF260

0.022

CF280

0.029

Cyanine7 NHS ester()Related Product Information

• Cyanine7 amine
• Cyanine7 dicarboxylic acid
• Cyanine7 maleimide
• Cyanine7 DBCO
• Cyanine7 hydrazide
• Cyanine7 carboxylic acid
• Cyanine7 azide
• Cyanine7 alkyne
• Sulfo-Cyanine7 NHS ester
• CY7-Sulfo NHS Ester