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Nifedipine Impurity J

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Nifedipine Impurity J Basic information

Product Name:
Nifedipine Impurity J
Synonyms:
  • Nifedipine Monoamide
  • XWBOVLISSVULHY-UHFFFAOYSA-N
  • 5-(Aminocarbonyl)-1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3-pyridinecarboxylic Acid Methyl Ester, Nifedipine Impurity 1
  • Nifedipine EP Impurity E
  • Nifedipine Impurity J
  • methyl 5-carbamoyl-2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3-carboxylate
  • Nifedipine Amide Impurity
  • 3-Pyridinecarboxylic acid, 5-(aminocarbonyl)-1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, methyl ester
CAS:
114709-68-1
MF:
C16H17N3O5
MW:
331.32
Mol File:
114709-68-1.mol
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Nifedipine Impurity J Chemical Properties

Melting point:
>140°C (dec.)
Boiling point:
538.8±50.0 °C(Predicted)
Density 
1.309±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pka
15.20±0.70(Predicted)
form 
Solid
color 
Orange
Stability:
Hygroscopic
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Nifedipine Impurity J Usage And Synthesis

Uses

Nifedipine Monoamide is an impurity of Nifedipine (N457000); a dihydropyridine calcium channel blocker. Also used as an antihypertensive and antianginal.

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