Prucalopride Impurity 1 Chemical Properties

Boiling point:

527.2±50.0 °C(Predicted)

Density 

1.29±0.1 g/cm3(Predicted)

pka

13.13±0.20(Predicted)

Prucalopride Impurity 1 Usage And Synthesis

Uses

4-?Amino-?5-?chloro-?N-?[1-?(3-?methoxypropyl)?-?4-?piperidinyl]?-7-?benzofurancarboxamid?e is an impurity of Prucalopride Succinate (P838950(P)), which is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe. In a more recent analytical study, 4-?Amino-?5-?chloro-?N-?[1-?(3-?methoxypropyl)?-?4-?piperidinyl]?-7-?benzofurancarboxamid?e was selectively separated and characterized as a process impurity of Prucalopride Succinate (P838950(P)) under stress conditions.

Prucalopride Impurity 1(1900715-96-9)Related Product Information

• Prucalopride Impurity 32
• Methyl 4-(acetylaMino)-3-broMo-2-(2-broMoethoxy)-5-chlorobenzoate
• Prucalopride Impurity 10/ethyl 4-(4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxamido)piperidine-1-carboxylate
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