Shizukaol B
Shizukaol B Basic information
- Product Name:
- Shizukaol B
- Synonyms:
-
- Shizukaol B
- Propanoic acid, 2-[(3R,3aS,3bR,4aS,5aS,6S,6aR,7aS,8S,12E,24aS,24bR,27R)-3,3a,3b,4,4a,5,5a,6,6a,7,7a,8,9,11,14,16,17,18,19,24b-eicosahydro-3,8-dihydroxy-3a,6,12-trimethyl-2,11,16,19,23-pentaoxo-23H-6,8,24a,22-[1]propanyliden[3]ylidyne-21H,24aH-cyclopropa[r]cycloprop[1,2]acenaphtho[4,5-u][1,5,10,15]te...
- CAS:
- 142279-40-1
- MF:
- C40H44O13
- MW:
- 732.77
- Mol File:
- 142279-40-1.mol
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Shizukaol B Usage And Synthesis
Uses
Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-α, and IL-1β expression[1].
IC 50
COX-2; iNOS; IL-1β
References
[1] Pan LL, et al. Shizukaol B, an active sesquiterpene from Chloranthus henryi, attenuates LPS-induced inflammatory responses in BV2 microglial cells. Biomed Pharmacother. 2017 Apr;88:878-884. DOI:10.1016/j.biopha.2017.01.152
Shizukaol BSupplier
BioBioPha Co., Ltd.
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ANHUI WITOP BIOTECH CO., LTD
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