Zofluza intermediate Chemical Properties

Boiling point:

379.5±42.0 °C(Predicted)

Density 

1.400±0.06 g/cm3(Predicted)

pka

12.57±0.20(Predicted)

InChI

InChI=1S/C14H10F2OS/c15-11-6-5-8-10(13(11)16)7-18-12-4-2-1-3-9(12)14(8)17/h1-6,14,17H,7H2

InChIKey

OBEXFUFBCNVOKB-UHFFFAOYSA-N

SMILES

S1CC2=C(F)C(F)=CC=C2C(O)C2=CC=CC=C12

Zofluza intermediate Usage And Synthesis

Uses

7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-ol is an impurity of Baloxavir Marboxil (B116325) which is an inhibitor of the cap-dependent endonuclease of influenza A and B viruses.

Zofluza intermediate(1985607-83-7)Related Product Information

• Baloxavir marboxil
• Baloxavir Impurity 5
• Baloxavir
• (R)-7-(benzyloxy)- 3,4,12,12a-tetrahydro- 1H-[1,4]oxazino[3,4- c]pyrido[2,1-f][1,2,4]- triazine-6,8-dione
• (12aR)-7-(hexyloxy)-3,4,12,12a-tetrahydro-1H-[1,4]Oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione
• BAY 299
• T-26c
• AZD-7594
• 4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile
• ABBV-744
• RGX-104 HCl
• Adavivint
• 4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)-
• 3-(BENZYLOXY)-2-METHYL-4H-PYRAN-4-ONE
• 7-(Benzyloxy)-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione
• Zoledronic acid
• 7,8-difluorodibenzo[b,e]thiepin-11(6H)-one
• 1-amino-3-(benzyloxy)-4-oxo-N-(2-(2-oxoethoxy)ethyl)-1,4-dihydropyridine-2-carboxamide