Moroxydine Chemical Properties

Melting point:

211-214 °C(lit.)

Boiling point:

274.0±50.0 °C(Predicted)

Density 

1.51±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

pka

13.01±0.10(Predicted)

Merck 

13,6295

CAS DataBase Reference

3731-59-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39-36

WGK Germany 

3

HazardClass 

IRRITANT

Moroxydine Usage And Synthesis

Originator

Grippe,Nissin

Uses

antiviral

Definition

ChEBI: N-(diaminomethylidene)-4-morpholinecarboximidamide is a member of biguanides.

Manufacturing Process

43.5 g morpholine, 41.7 ml concentrated hydrochloric acid, 40 ml of water, and 42 g dicyandiamide are refluxed for 48 hours, whereupon the reaction mixture is cooled to +5°C and filtered. The filtrate is evaporated to dryness and extracted and extracted with boiling ethanol. Yield: 50 g. The formed 4- morpholinecarboximidoylguanidine hydrochloride is purified by recrystallization from methanol. The salt may be converted into the base by adding equivalent of any basic compound (triethylamine, sodium bicarbonate and so on).
In practice it is usually used as hydrochloride.

Therapeutic Function

Antiviral

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