Ceftriaxone sodium
Ceftriaxone sodium Basic information
- Product Name:
- Ceftriaxone sodium
- Synonyms:
-
- (6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-Methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]Methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid SodiuM Salt Hydrate
- Ceftriaxone sodiuM sesquaterhydrate
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, sodium salt, hydrate (2:4:7), (6R,7R)-
- Ceftriaxone SodiuM Trihydrate
- Ceftriaxone disodium salt hemiheptahydrate, >=98%
- sodium 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, sodium salt, hydrate (2:
- Ceftriaxone (sodium salt hydrate)
- CAS:
- 104376-79-6
- MF:
- C18H21N8NaO8S3
- MW:
- 596.58
- EINECS:
- 626-956-4
- Product Categories:
-
- VESPRIN
- Antibiotics for Research and Experimental Use
- API
- beta-Lactams (Antibiotics for Research and Experimental Use)
- Biochemistry
- Antibiotic Explorer
- Intermediates & Fine Chemicals
- Pharmaceuticals
- A - KAntibiotics
- Antibacterial
- Antibiotics A to
- Antibiotics A-FAntibiotics
- Chemical Structure Class
- Interferes with Cell Wall SynthesisAntibiotics
- Mechanism of Action
- Penicillins and Cephalosporins (beta-Lactams)
- Spectrum of Activity
- Ceftriaxone
- Heterocycles
- Sulfur & Selenium Compounds
- Mol File:
- 104376-79-6.mol
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Ceftriaxone sodium Chemical Properties
- Melting point:
- 236 °C
- alpha
- D25 -165° (c = 1 in water) (calc for water-free substance)
- refractive index
- -160 ° (C=1, H2O)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- H2O: soluble50mg/mL
- pka
- ~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH)
- form
- powder or crystals
- color
- White to Off-White
- Water Solubility
- Freely soluble in water
- InChIKey
- FDRNWTJTHBSPMW-BBJOQENWSA-L
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-42/43
- Safety Statements
- 26-36-45-37-24-22
- WGK Germany
- 1
- RTECS
- XI0368800
- HS Code
- 29349990
- Toxicity
- LD50 in male, female, mice, rats (mg/kg): 3000, 2800, 2175, 2175 i.v.; >10000 all species orally; >5000 all species s.c. (Teelman)
MSDS
- Language:English Provider:SigmaAldrich
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Ceftriaxone sodium Usage And Synthesis
Description
Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.
Chemical Properties
White Crystalline Solid
Uses
antipsychotic
Uses
A potentially useful antibacterial agent for proteomics research.
Uses
An antibacterial, a third-generation cephalosporin.
Definition
ChEBI: Ceftriaxone disodium salt hemiheptahydrate is a cephalosporin.
brand name
Rocephin (Roche).
Biological Activity
β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter.
Ceftriaxone sodiumSupplier
Wuhan Yuqing Jiaheng Pharmaceutical Co., Ltd Gold
- Tel
- 027-83855382 15926260338
- 15926260338@163.com
Hubei widely chemical technology Co., Ltd. Gold
- Tel
- 027-83991130 18627774460
- 1718093273@QQ.COM
Wuhan Fortuna Chemical Co., Ltd Gold
- Tel
- 027-59207852 13308628970
- buy@fortunachem.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
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Ceftriaxone sodium(104376-79-6)Related Product Information
- (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Thiotriazinone
- Cephalothin sodium
- Cefotaxime sodium
- 3-Desacetyl CefotaxiMe Lactone
- (E)-Ceftriaxone
- Ceftriaxone Sodium intermediate
- CEFTRIAXONE SODIUM, USP
- Ceftriaxone sodium
- CEFTRIAXONE IMPURITY A
- CEFTRIAXONE SODIUM E-ISOMER (25 MG)
- Ceftriaxone Sodium sterile USP/EP/JP
- Ceftriaxone sodium Non sterile(crude)
- Ceftriaxone sodium (crude) In-house Spec 25kg/box
- Ceftriaxone sodium (solvent crystallization of sterile BPC) CHP 、USP、EP 5kg/tin、2tin/box
- Ceftriaxone sodium crude,non-sterile,crystalline,sterile
- Ceftriaxone sodium crystalline.sterile
- 7-ACT / for Ceftriaxone Sodium