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1-Naphthyl acetate

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1-Naphthyl acetate Basic information

Product Name:
1-Naphthyl acetate
Synonyms:
  • 1-naphthylacetae
  • aceticacidnaphthalen-1-ylester
  • alpha-naphtholacetate
  • Naphthalene, 1-acetoxy-
  • 1-NAPHTHYL ACETATE
  • ACETIC ACID 1-NAPHTHYL ESTER
  • ACETIC ACID ALPHA-NAPHTHYL ESTER
  • 1-Acetoxynaphthalene
CAS:
830-81-9
MF:
C12H10O2
MW:
186.21
EINECS:
212-599-8
Product Categories:
  • Intermediates of Dyes and Pigments
  • Aromatic Esters
  • Cytochemistry Products
  • Hematology and Histology
Mol File:
830-81-9.mol
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1-Naphthyl acetate Chemical Properties

Melting point:
43-46 °C (lit.)
Boiling point:
118 °C / 1mmHg
Density 
1.1032 (rough estimate)
refractive index 
1.6010 (estimate)
Flash point:
113 °C
storage temp. 
-20°C
solubility 
dioxane: 0.1 g/mL, clear, colorless
form 
Crystalline Powder or Crystals
color 
White to light yellow or slightly pink
Odor
Odorless
Sensitive 
Moisture Sensitive
BRN 
2046403
CAS DataBase Reference
830-81-9(CAS DataBase Reference)
NIST Chemistry Reference
1-Naphthyl acetate(830-81-9)
EPA Substance Registry System
1-Naphthyl acetate (830-81-9)
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Safety Information

Hazard Codes 
T,Xi
Risk Statements 
41-39/23/24/25-23/24/25-10
Safety Statements 
26-39-24/25-22-45-36/37-16
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
QL2975500
10-21
TSCA 
Yes
HS Code 
29153900

MSDS

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1-Naphthyl acetate Usage And Synthesis

Chemical Properties

1-Naphthyl acetate is white to light yellowish or slightly pink

Uses

1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors.

Uses

1-Naphthyl Acetate is used in preparation method for synthesizing Ph Acetate derivative by Acetylation of Phenol compound.

Uses

1-Naphthyl acetate may be used in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It may be employed as substrate to investigate the distribution of non-specific carboxylic esterases (EC 3.1.1) in the digestive tract of perch, Perm fliiviatilis L.

Synthesis Reference(s)

Synthetic Communications, 21, p. 989, 1991 DOI: 10.1080/00397919108019787
Tetrahedron Letters, 30, p. 95, 1989 DOI: 10.1016/S0040-4039(01)80332-4

General Description

1-Naphthyl acetate is a 1-napthyl ester. Mechanism of photo-Fries rearrangement of 1-naphthyl acetate has been studied using steady state photolysis and laser flash photolysis. Kinetics of photo-Fries rearrangement of 1-napthyl acetate has been studied using steady-state, time-resolved chemically induced dynamic nuclear polarization (CIDNP) and flash photolysis methods.

Purification Methods

Chromatograph the acetate on silica gel and crystallise as the 2-isomer below. The 2,4,7-trinitrofluoren-9-one complex has m 120o (from EtOH). [Beilstein 6 H 608, 6 III 2928, 6 IV 4217.]

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