ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Amide > 4'-CHLOROACETANILIDE
4'-CHLOROACETANILIDE
4'-CHLOROACETANILIDE Basic information
- Product Name:
- 4'-CHLOROACETANILIDE
- Synonyms:
-
- ACETIC ACID 4-CHLOROANILIDE
- ACETAMINOPHEN IMPURITY J
- ACETAMINOPHENE IMP J
- 4'-CHLOROACETANILIDE
- 4-CHLOROACETANILIDE
- 4-CHLORACETANILIDE
- LABOTEST-BB LT00792311
- P-CHLOROACETANILIDE
- CAS:
- 539-03-7
- MF:
- C8H8ClNO
- MW:
- 169.61
- EINECS:
- 208-707-8
- Product Categories:
-
- Amines
- Aromatics
- Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
- Anilines, Amides & Amines
- Chlorine Compounds
- Mol File:
- 539-03-7.mol
More
Less
4'-CHLOROACETANILIDE Chemical Properties
- Melting point:
- 176-178 °C(lit.)
- Boiling point:
- 333 °C
- Density
- 1,385 g/cm3
- refractive index
- 1.5670 (estimate)
- Flash point:
- 333°C
- storage temp.
- 2-8°C
- solubility
- dioxane: 50 mg/mL hot, clear
- pka
- 14.25±0.70(Predicted)
- form
- Crystalline Powder
- color
- White or grayish-beige
- Water Solubility
- Insoluble in water.
- Merck
- 14,2111
- BRN
- 509638
- CAS DataBase Reference
- 539-03-7(CAS DataBase Reference)
- EPA Substance Registry System
- 4-Chloroacetanilide (539-03-7)
More
Less
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- AE1001000
- TSCA
- Yes
- HS Code
- 29242990
- Hazardous Substances Data
- 539-03-7(Hazardous Substances Data)
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
More
Less
4'-CHLOROACETANILIDE Usage And Synthesis
Chemical Properties
white or greyish-beige crystalline powder
Uses
4'-Chloroacetanilide is used in pharmaceutical preparations, using PGC column. And also used in the synthesis of alprazolam.
Definition
ChEBI: Acetamide substituted on nitrogen by a para-chlorophenyl group.
Synthesis Reference(s)
Tetrahedron, 52, p. 8863, 1996 DOI: 10.1016/0040-4020(96)00433-4
General Description
4′-Chloroacetanilide is the main impurity present in acetaminophen and has been quantitated by new high-performance liquid chromatography method using a mixed-mode reversed-phase/cation exchange stationary phase.
Purification Methods
Crystallise the anilide from EtOH or aqueous EtOH. [Beilstein 12 IV 1178.]
4'-CHLOROACETANILIDESupplier
Shandong RuiYue Biotechnology Co., Ltd. Gold
- Tel
- 0531-88581623 18805314509
- 1456922171@126.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
Alfa Aesar
- Tel
- 400-6106006
- saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
More
Less
4'-CHLOROACETANILIDE(539-03-7)Related Product Information
- 2-Acetamidophenol
- ACETAMINOPHEN IMPURITY B
- 4,4'-Iminodiphenol hydrochloride
- 4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one
- 4'-Hydroxyacetophenone
- 3-CHLORO-4-HYDROXYACETANILIDE
- 2'-Hydroxyacetophenone
- 4-Acetoxyacetanilide
- N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE
- Acetanilide
- 1-(2,4,6-Trichlorophenyl)-3-amino-pyrazolin-5-one
- 2-Chloro-N-[4-chloro-2-(2-chlorobenzoyl)phenyl]acetamide
- N-(4-Chlorophenyl)-2-chloroacetamide
- Propanil
- 4'-Chloro-2'-methylacetoacetanilide
- 5-Chloroisatin
- 5-BROMO-4'-CHLOROSALICYLANILIDE
- 3',5'-BIS(TRIFLUOROMETHYL)-2-CHLOROACETANILIDE