Syringic acid
Syringic acid Basic information
- Product Name:
- Syringic acid
- Synonyms:
-
- RARECHEM AL BE 0102
- SYRINGIC ACID
- 4-Hydroxy-3,5-dimethoxybenzoic acid for synthesis
- Benzoic acid, 4-hydroxy-3,5-dimethoxy-
- Cedar acid
- cedaracid
- GALLIC ACID 3,5-DIMETHYL ETHER
- LABOTEST-BB LT00454715
- CAS:
- 530-57-4
- MF:
- C9H10O5
- MW:
- 198.17
- EINECS:
- 208-486-8
- Product Categories:
-
- FINE Chemical & INTERMEDIATES
- Inhibitors
- chemical reagent
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
- Benzoic acid
- Organic acids
- Acids & Esters
- Anisoles, Alkyloxy Compounds & Phenylacetates
- Phenols
- Pharmaceutical Intermediate
- Mol File:
- 530-57-4.mol
Syringic acid Chemical Properties
- Melting point:
- 205-209 °C (lit.)
- Boiling point:
- 192-193°C 14mm
- Density
- 1.2539 (rough estimate)
- refractive index
- 1.4570 (estimate)
- Flash point:
- 192-193°C/14mm
- storage temp.
- Store below +30°C.
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.33±0.10(Predicted)
- form
- Powder
- color
- Grayish-beige to light brown
- Water Solubility
- 5780 mg/L (25 ºC)
- BRN
- 2115262
- Stability:
- Stable. Incompatible with strong bases, strong oxidizing agents.
- InChIKey
- JMSVCTWVEWCHDZ-UHFFFAOYSA-N
- LogP
- 1.040
- CAS DataBase Reference
- 530-57-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzoic acid, 4-hydroxy-3,5-dimethoxy-(530-57-4)
- EPA Substance Registry System
- Syringic acid (530-57-4)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- DH2090000
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29189090
MSDS
- Language:English Provider:3,5-Dimethoxy-4-hydroxybenzoic acid
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
Syringic acid Usage And Synthesis
Description
Syringic acid is a naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol. It is also a component of phenolic extracts from various plants that have antioxidant and prooxidant activities. Syringic acid has been shown to inhibit aldose reductase (IC50 = 213 μg/ml), proteasome activity, and cancer cell proliferation. Phenolic extracts containing syringic acid have been shown to inhibit α-amylase and α-glucosidase activities and reduce lipid peroxidation in vitro.
Chemical Properties
light brown powder
Uses
antiproliferative; antifungal
Uses
Syringic Acid is used in biological studies for electron transfer from plant phenolates to carotenoid radical cations with antioxidant interaction entering the Marcus theory inverted region.
Definition
ChEBI: A dimethoxybenzene that is 3,5-dimethyl ether derivative of gallic acid.
Purification Methods
Recrystallise syringic acid from H2O using charcoal [Bogert & Coyne J Am Chem Soc 51 571 1929, Anderson & Nabenhauer J Am Chem Soc 48 3001 1926.] The methyl ester has m 107o (from MeOH), the 4-acetyl derivative has m 190o and the 4-benzoyl derivative has m 229-232o. [Hahn & Wassmuth Chem Ber 67 2050 1934, UV: Lemon J Am Chem Soc 69 2998 1947 and Pearl & Beyer J Am Chem Soc 72 1743 1950, Beilstein 10 IV 1995.]
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Syringic acid(530-57-4)Related Product Information
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