3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE Chemical Properties

Boiling point:

65 °C

Density 

0.965 g/mL at 25 °C

Flash point:

1 °F

storage temp. 

2-8°C

form 

Solution

color 

Yellow to dark brown

Water Solubility 

Reacts with water.

Sensitive 

Air & Moisture Sensitive

Safety Information

Hazard Codes 

F,C,Xn

Risk Statements 

11-14-19-22-34-40-36/37

Safety Statements 

16-26-33-36/37/39-45-36/37

RIDADR 

UN 2924 3/PG 2

WGK Germany 

1

Hazard Note 

Flammable

HazardClass 

3

HS Code 

29319090

MSDS

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3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE Usage And Synthesis

Chemical Properties

Tan liquid

Uses

3,4-Difluorophenylmagnesium bromide, 0.50 M in 2-MeTHF is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.

Uses

3,4-Difluorophenylmagnesium bromide can be used:

• To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.
• In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.
• In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.
• In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.

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