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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Pyrimidines >  Aminopyrimidine >  (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL

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(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL Basic information

Product Name:
(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL
Synonyms:
  • 4-AMINO-2-(METHYLTHIO)-5-PYRIMIDINEMETHANOL
  • 4-AMINO-5-HYDROXYMETHYL-2-(METHYLTHIO)PYRIMIDINE
  • Methioprim
  • (4-azanyl-2-methylsulfanyl-pyrimidin-5-yl)methanol
  • (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL
  • (4-AMINO-2-METHYLSULFANYL-PYRIMIDIN-5-YL)-METHANOL
  • 4-AMINO-2-METHYLMERCAPTO-PYRIMIDINE-4-CARBINOL
  • (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)ME...
CAS:
588-36-3
MF:
C6H9N3OS
MW:
171.22
Product Categories:
  • Amines
  • Aromatics
  • Heterocycles
  • Sulfur & Selenium Compounds
Mol File:
588-36-3.mol
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(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL Chemical Properties

Melting point:
126-127°
Boiling point:
408.6±30.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13.08±0.10(Predicted)
color 
Off-White to Pale Yellow
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Safety Information

HS Code 
29335990
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(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL Usage And Synthesis

Chemical Properties

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL is white cryst powder

Uses

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL is an intermediate used in the synthesis of Thiamine (T344185). Also, used for the preparation of pyridopyrimidines and naphthyridines as inhibitors of Akt kinase for the treatment of cancer.

Uses

Tumor antagonist in mice.

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