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METHYL 2-FLUORO-4-NITROBENZENECARBOXYLATE

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METHYL 2-FLUORO-4-NITROBENZENECARBOXYLATE Basic information

Product Name:
METHYL 2-FLUORO-4-NITROBENZENECARBOXYLATE
Synonyms:
  • METHYL 2-FLUORO-4-NITROBENZENECARBOXYLATE
  • METHYL 2-FLUORO-4-NITROBENZOATE
  • 3-Fluoro-4-(methoxycarbonyl)nitrobenzene
  • Benzoic acid, 2-fluoro-4-nitro-, Methyl ester
  • Benzoic acid, 2-fluoro-4-nitro-, methyl ester (8CI, 9CI, ACI)
  • 2-fluoro-4-nitro-Benzoic acid methyl ester (8CI 9CI ACI)
CAS:
392-09-6
MF:
C8H6FNO4
MW:
199.14
EINECS:
206-873-6
Mol File:
392-09-6.mol
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METHYL 2-FLUORO-4-NITROBENZENECARBOXYLATE Chemical Properties

Melting point:
73-75°C
Boiling point:
314.6±32.0 °C(Predicted)
Density 
1.388
storage temp. 
Sealed in dry,Room Temperature
form 
crystalline solid
color 
Pale lemon
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Safety Information

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2916399090
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METHYL 2-FLUORO-4-NITROBENZENECARBOXYLATE Usage And Synthesis

Uses

Methyl 2-fluoro-4-nitrobenzoate is a pharmaceutical intermediate compound used in the preparation of the anticancer drug Venetoclax.  Venetoclax is a B-cell lymphoma-2 (BCL-2) inhibitor used in the treatment of adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL), or newly diagnosed chronic lymphocytic lymphoma (SLL).

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