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(S)-(+)-4-Phenyl-2-oxazolidinone

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(S)-(+)-4-Phenyl-2-oxazolidinone Basic information

Product Name:
(S)-(+)-4-Phenyl-2-oxazolidinone
Synonyms:
  • (4S)-4-PHENYL-1,3-OXAZOLIDIN-2-ONE
  • 4-S-PHENYL-OXAZOLIDIN-2-ONE
  • (4S)-PHENYL-2-OXAZOLIDINONE
  • L-(+)-4-(4S)-PHENYLOXAZOLIDINONE
  • (S)-PH-OXAZOLIDINONE
  • SPOX
  • S-POA
  • (S)-(+)-4-PHENYLOXAZOLIDIN-2-ONE
CAS:
99395-88-7
MF:
C9H9NO2
MW:
163.17
EINECS:
619-429-5
Product Categories:
  • Asymmetric Synthesis
  • Chiral Auxiliaries
  • Glycidyl Compounds, etc. (Chiral)
  • Synthetic Organic Chemistry
  • Chiral chemicals
  • Oxazolidinone Derivatives
  • Oxazolidinone
  • Chiral Compounds
  • chiral
  • Chiral Reagent
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Peptide
  • 99395-88-7
Mol File:
99395-88-7.mol
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(S)-(+)-4-Phenyl-2-oxazolidinone Chemical Properties

Melting point:
129-132 °C(lit.)
alpha 
49.5 º (c=2, CHCl3)
Boiling point:
290.25°C (rough estimate)
Density 
1.2021 (rough estimate)
refractive index 
72 ° (C=1, AcOEt)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
12.05±0.40(Predicted)
form 
Crystalline Powder
color 
White
optical activity
[α]20/D +48°, c = 2 in chloroform
BRN 
131918
InChIKey
QDMNNMIOWVJVLY-MRVPVSSYSA-N
CAS DataBase Reference
99395-88-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,F+
Risk Statements 
12-36
Safety Statements 
24/25-33-26-16-7/9
WGK Germany 
3
3-9
HS Code 
29349990

MSDS

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(S)-(+)-4-Phenyl-2-oxazolidinone Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

Ezetimibe intermediate

Uses

Versatile chiral auxiliary for asymmetric synthesis which is easily recycled under mild conditions, thus enhancing its commercial potential. For a recent review, see Aldrichimica Acta .

Uses

S)-4-Phenyl-2-oxazolidinone is an intermediate for the synthesis and development for cholesterol absorption inhibitor AZD4121.

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