N-(tert-Butoxycarbonyl)-O-benzyl-D-threonine Chemical Properties

Melting point:

110-117°C

Boiling point:

461.5±45.0 °C(Predicted)

Density 

1.152±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Solid

pka

3.50±0.10(Predicted)

color 

White to off-white

optical activity

-20.2° (C=1.00 g/100ml ETOH)

BRN 

7339503

Major Application

peptide synthesis

InChI

1S/C16H23NO5/c1-11(21-10-12-8-6-5-7-9-12)13(14(18)19)17-15(20)22-16(2,3)4/h5-9,11,13H,10H2,1-4H3,(H,17,20)(H,18,19)

InChIKey

CTXPLTPDOISPTE-WCQYABFASA-N

SMILES

N(C(C(OCc1ccccc1)C)C(=O)O)C(=O)OC(C)(C)C

CAS DataBase Reference

69355-99-3(CAS DataBase Reference)

Safety Information

WGK Germany 

3

HS Code 

2924 29 70

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:SigmaAldrich

N-(tert-Butoxycarbonyl)-O-benzyl-D-threonine Usage And Synthesis

Uses

Boc-D-Thr(Bzl)-OH, is an amino acid derivative that can be used in the synthesis of millepachine amino acid prodrugs with enhanced solubility as antitumor agents.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

N-(tert-Butoxycarbonyl)-O-benzyl-D-threonine(69355-99-3)Related Product Information

• N-Boc-(S)-2-amino-3-benzyloxy-1-propanol
• (R)-2-Amino-3-methoxylpropanoic acid
• N-BOC-O-Benzyl-L-serine
• N-BOC-SERINOL, 97
• D-Serine
• Boc-D-Serine
• BOC-D-ABU-OH
• O-BENZYL-DL-SERINE
• Boc-O-Benzyl-D-threoninol
• D-Threonine
• BOC-D-Alanine
• DL-Threonine hydrate(2:1)
• N-Boc-D-alaninol
• Boc-o-methyl-D-serine
• N-(tert-Butoxycarbonyl)-O-benzyl-D-threonine
• BOC-D-THR-OH
• 3-BENZYLOXY-PROPIONALDEHYDE
• Boc-Thr(Bzl)-OH