2-Chloromethyl-3,4-dimethoxypyridinium chloride Chemical Properties

Melting point:

155 °C (dec.)(lit.)

storage temp. 

Inert atmosphere,Room Temperature

Water Solubility 

Soluble in water

solubility 

Chloroform (Slightly, Heated), Methanol (Very Slightly)

form 

powder to crystal

color 

White to Orange to Green

BRN 

5360726

InChI

InChI=1S/C8H10ClNO2.ClH/c1-11-7-3-4-10-6(5-9)8(7)12-2;/h3-4H,5H2,1-2H3;1H

InChIKey

YYRIKJFWBIEEDH-UHFFFAOYSA-N

SMILES

C1(CCl)=[NH+]C=CC(OC)=C1OC.[Cl-]

CAS DataBase Reference

72830-09-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,N,Xi

Risk Statements 

21/22-38-41-43-48/22-51/53

Safety Statements 

26-36/37/39-61-2

RIDADR 

UN 3077 9/PG 3

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

9

PackingGroup 

III

HS Code 

2933399932

MSDS

• Language:English Provider:SigmaAldrich

2-Chloromethyl-3,4-dimethoxypyridinium chloride Usage And Synthesis

Chemical Properties

Light Brown Solid

Uses

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride may be used as a precursor for the preparation [(2-pyridyl)-2-ethyl]-[3,4-dimethoxy-(2-pyridylmethyl)]-N-methylamine.

General Description

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride (CDP) can be synthesized using maltol as a starting material. CDP and DMS (dimethyl sulfate) are used in the preparation of pantoprazole sodium (PPS), an antiulcerative drug. The quantification of CDP and DMS in PPS can be done simultaneously by gas chromatography–mass spectrometry (GC-MS) method.

2-Chloromethyl-3,4-dimethoxypyridinium chloride(72830-09-2)Related Product Information

• N-Methyl Pantoprazole, mixture of 1 and 3 isomers
• 4-Methoxybenzoic acid
• Ufiprazole
• 2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole
• 2-Chloromethyl-4-methoxy-3,5-dimethylpyridine hydrochloride
• 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
• 2-Hydroxymethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride
• Sodium erythorbate
• 2-Chloromethyl-3-methyl-4-(3-methoxypropoxy)pyridine hydrochloride
• 2-(2-AMINO-5-BROMOBENZOYL) PYRIDINE
• 4-Difluoromethoxy-2-nitro-aniline
• N-[4-(difluoromethoxy)-2-nitrophenyl]acetamide
• Pantoprazole Impurity 11
• 4,4'-Bis(chloromethyl)-2,2'-bipyridyl
• Pantoprazole Sulfide Dimer
• PANTOPRAZOLE SULFONE N-OXIDE
• N-[(3,4-DiMethoxy-2-pyridinyl)Methyl] Pantoprazole Sulfide
• Pantoprazole Impurity 7