4-BROMO-4'-PROPYLBIPHENYL Chemical Properties

Melting point:

107-109°C

Boiling point:

349.5±21.0 °C(Predicted)

Density 

1.249±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

almost transparency in Toluene

form 

powder to crystal

color 

White to Light yellow

CAS DataBase Reference

58743-81-0(CAS DataBase Reference)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HS Code 

2903.99.8001

4-BROMO-4'-PROPYLBIPHENYL Usage And Synthesis

Chemical Properties

4-BROMO-4'-PROPYLBIPHENYL is White crystalline

Uses

4-BROMO-4'-PROPYLBIPHENYL is an intermediate used in the synthesis of a series of cyanobiphenyls which are liquid crystal materials.

Synthesis

General procedure for the synthesis of 4-bromo-4'-propylbiphenyl from 4-n-propylbiphenyl: To a reaction flask was added 1 equiv. of 4-n-propylbiphenyl (Compound 5), methylene chloride (the fifth organic solvent), and 0.2 equiv. of ferric chloride, wherein the ratio of methylene chloride to 4-n-propylbiphenyl by weight was 5:1. The mixture was stirred thoroughly, 1.15 equiv. of liquid bromine was added slowly, and the reaction temperature was The reaction temperature was maintained at 25 °C and the reaction time was 18 hours. Upon completion of the reaction, the reaction was quenched by the addition of 15% aqueous sodium hydroxide, stirred and left to separate. The organic phase was washed twice with water to remove the aqueous phase. Subsequently, the organic phase was dried to give the crude product 4-bromo-4'-propylbiphenyl (compound 6). The crude product was pulped in methanol, filtered and dried to give 4-bromo-4'-propylbiphenyl (compound 6) as a white solid in 77% yield.

References

[1] Patent: CN108129258, 2018, A. Location in patent: Paragraph 0020; 0030; 0031; 0038; 0039; 0040; 0041; 0042

4-BROMO-4'-PROPYLBIPHENYL(58743-81-0)Related Product Information

• Naphthalene
• 4-Propylbiphenyl
• 4-Propylbiphenyl
• 4-BROMO-4'-N-PENTYLBIPHENYL
• Bromadiolone
• 4-BROMO-4'-(4-OCTYLPHENETHYL)-1,1'-BIPHENYL
• Brodifacoum
• DIFETHIALONE
• 3-(4'-Bromo[1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenol
• 4''-BUTYL-4-BROMO-3-FLUOROBIPHENYL
• 4''-PENTYL-4-BROMO-3-FLUOROBIPHENYL
• 4''-PROPYL-4-BROMO-3-FLUOROBIPHENYL
• 4-BROMO-4'-PROPYLBIPHENYL
• 4-BROMO-4'-N-HEPTYLBIPHENYL